A High-Sensitivity UPLC/MS/MS Method for the Quantification of Desmpressin in Rat Plasma

نویسندگان

  • P.M.N. Rajesh
  • Gopal Vaidyanathan
چکیده

IN T RODUC T ION Desmopressin (1-desamino-8-D-arginine vasopressin), Figure 1, (trade names: DDAVP, Stimate, Minirin) is a peptide containing nine amino acids, a form of the normal human hormone arginine vasopressin that reduces urine production. It may be taken nasally, intravenously, or as a tablet. Desmopressin is most commonly prescribed for the treatment of diabetes insipidus or nocturnal enuresis.

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تاریخ انتشار 2011